SAB4502745

Anti-SFRP2 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): FRP-2, Frizzled-related protein 2, SARP-1, Secreted apoptosis-related protein 1, sFRP-2
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 33 kDa
• Speziesreaktivität: rat, mouse, human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:5000; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: Q96HF1
• UniProt-Hinterlegungsnummer: Q96HF1
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... SFRP2(6423)

Beschreibung

Allgemeine Beschreibung

Anti-SFRP2 Antibody detects endogenous levels of total SFRP2 protein.

The SFRP2 (secreted frizzled related protein 2) gene is mapped to human chromosome 4q31.3. It is found to be expressed in sclerotome.

Immunogen

The antiserum was produced against synthesized peptide derived from human SFRP2.

Immunogen Range: 119-168

Biochem./physiol. Wirkung

SFRP2 (secreted frizzled related protein 2) promotes phosphorylation and retards the expression of nuclear β-catenin and inhibits the canonical Wnt signaling pathway. SFRP2 is known to enhance osteogenic differentiation in mesenchymal stem cells.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable