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Merck

SAB4500367

Sigma-Aldrich

Anti-Collagen III antibody produced in rabbit

affinity isolated antibody

Synonym(e):

COL3A1, Collagen α-1(III) chain

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 138 kDa

Speziesreaktivität

mouse, human, rat

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... COL3A1(1281)

Allgemeine Beschreibung

Anti-Collagen III Antibody detects endogenous levels of total Collagen III protein.
Collagen III is also termed as collagen type III α1 (COL3A1). It is a fibrillar collagen present in extensible connective tissues. COL3A1 spans around 44 kb in length and has 52 exons. It is expressed in blood vessels and hollow organs. Collagen III gene is located on human chromosome 2q32.2.

Immunogen

The antiserum was produced against synthesized peptide derived from human Collagen III.

Immunogen Range: 81-130

Anwendung

Anti-Collagen III antibody has been used in immunohistochemistry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Biochem./physiol. Wirkung

Collagens usually help in the development of fibrillar and microfibrillar networks of the extracellular matrix, basement membranes and structures of the extracellular matrix. Mutations in the COL3A1 gene results in vascular ehlers-danlos syndrome (vEDS). COL3A1 controls the expression and modulation of collagen.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Empfehlung

Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Eri Ohto-Fujita et al.
Cell and tissue research, 376(1), 123-135 (2018-11-19)
Signs of aging in facial skin correlate with lifespan and chronic disease; however, the health of aging skin has not been extensively studied. In healthy young skin, the dermis forms a type III collagen-rich dermal papilla, where capillary vessels supply
A new candidate substrate for cell-matrix adhesion study: the acellular human amniotic matrix.
Guo Q, et al.
BioMed Research International, 2012 (2012)
Yuqing Ge et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 119, 109429-109429 (2019-09-11)
Asthma is a common obstructive airway disease characterized by inflammation and remodeling with a progressive decline in lung function. Fangxiao Formula (FXF) is an herbal medicine that has achieved significant clinical benefits toward asthma patients, but the relevant mechanism has
Let-7d suppresses growth, metastasis, and tumor macrophage infiltration in renal cell carcinoma by targeting COL3A1 and CCL7.
Su B, et al.
Molecular Cancer, 13(1), 206-206 (2014)
miR-29a/b enhances cell migration and invasion in nasopharyngeal carcinoma progression by regulating SPARC and COL3A1 gene expression.
Qiu F, et al.
PLoS ONE, 10(3), e0120969-e0120969 (2015)

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