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Merck

SAB4300686

Sigma-Aldrich

Anti-CD3E antibody produced in rabbit

affinity isolated antibody

Synonym(e):

Anti-FLJ18683, Anti-T3E, Anti-TCRE

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

~21 kDa

Speziesreaktivität

mouse, rat, human

Konzentration

1 mg/mL

Methode(n)

western blot: 1:500-1:1000

Isotyp

IgG

Immunogene Sequenz

(D-L-Y-S-G)

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... CD3E(916)

Allgemeine Beschreibung

The antibody detects endogenous level of total CD3E protein.

Immunogen

Peptide sequence around aa. 197-201 ( D-L-Y-S-G), according to the protein NP_000724.1

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Zielbeschreibung

The CD3 complex mediates signal transduction.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Luciën E P M van der Vlugt et al.
The Journal of infectious diseases, 210(8), 1207-1216 (2014-05-06)
Chronic schistosome infections are associated with T-cell hyporesponsiveness and a strong regulatory network. Murine studies have shown that schistosome infections can induce regulatory CD1d(hi) B cells, which inhibit inflammatory responses. Here, we evaluated the influence of regulatory B cells (Bregs)
Rinat Sharir et al.
Cardiovascular research, 103(4), 585-596 (2014-06-27)
Ischaemic damage is associated with up-regulation of pro-inflammatory cytokines, as well as invasion of leucocytes and lymphocytes to the injured muscle. Regulatory T cells (Tregs) exert suppressive effects on several immune and non-immune cellular elements. We hypothesized that adoptive Treg
Isabel Poschke et al.
Cancer immunology, immunotherapy : CII, 63(10), 1061-1071 (2014-07-06)
Adoptive transfer of in vitro-expanded tumor-infiltrating lymphocytes (TIL) has shown great clinical benefit in patients with malignant melanoma. TIL therapy itself has little side effects, but conditioning chemo- or radiotherapy and postinfusion interleukin 2 (IL-2) injections are associated with severe
Simon C Afford et al.
Hepatology (Baltimore, Md.), 59(5), 1932-1943 (2013-12-18)
Chronic hepatitis occurs when effector lymphocytes are recruited to the liver from blood and retained in tissue to interact with target cells, such as hepatocytes or bile ducts (BDs). Vascular cell adhesion molecule 1 (VCAM-1; CD106), a member of the
Jong Joo Lee et al.
Purinergic signalling, 10(2), 357-365 (2013-09-18)
This study investigated the immune-modulatory effects of human bone marrow-derived mesenchymal stem cells (hBMSCs) on human Th17 cell function through the CD39-mediated adenosine-producing pathway. The suppressive effects of hBMSCs were evaluated by assessing their effects on the proliferation of Th17

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