SAB4300282

Anti-phospho-SYK (pTyr³²³) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-DKFZp313N1010 antibody produced in rabbit, Anti-FLJ25043 antibody produced in rabbit, Anti-FLJ37489 antibody produced in rabbit, Anti-spleen tyrosine kinase antibody produced in rabbit
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~72 kDa
• Speziesreaktivität: human, rat, mouse
• Konzentration: 1 mg/mL
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• Isotyp: IgG
• Immunogene Sequenz: (N-P-YP-E-P)
• NCBI-Hinterlegungsnummer: NP_001128524.1
• UniProt-Hinterlegungsnummer: P43405
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr323)
• Angaben zum Gen: human ... SYK(6850)

Beschreibung

Allgemeine Beschreibung

Spleen tyrosine kinase (SYK) is a member of the non-receptor tyrosine kinase family. It is usually expressed in epithelial breast tissues and hematopoietic cells. The gene encoding it is localized on human chromosome 9q22.

Immunogen

Peptide sequence around phosphorylation site of tyrosine 323 (N-P-Y(p)-E- P), according to the protein SYK.

Biochem./physiol. Wirkung

Spleen tyrosine kinase (SYK) is a tumor suppressor gene that helps to prevent the development and metastasis of breast cancer cells. It participates in B-cell receptor signaling. The protein helps to phosphorylate the α-tubulin subunits of microtubules. SYK aids in the coupling of receptors for antigen-antibody complexes. It also modulates cell proliferation and differentiation.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable