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Key Documents

SAB4300168

Sigma-Aldrich

Anti-phospho-SYT1 (pSer309) antibody produced in rabbit

affinity isolated antibody

Synonym(e):

Anti-DKFZp781D2042 antibody produced in rabbit, Anti-P65 antibody produced in rabbit, Anti-SVP65 antibody produced in rabbit, Anti-SYT antibody produced in rabbit, Anti-synaptotagmin I antibody produced in rabbit

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About This Item

MDL-Nummer:
MFCD01865319
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

~46 kDa

Speziesreaktivität

human, rat, mouse

Konzentration

1 mg/mL

Methode(n)

indirect immunofluorescence: 1:100-1:200

Isotyp

IgG

Immunogene Sequenz

(G-L-SP-D-P)

NCBI-Hinterlegungsnummer

NP_001129277.1

UniProt-Hinterlegungsnummer

P21579

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

phosphorylation (pSer309)

Angaben zum Gen

human ... SYT1(6857)

Immunogen

Peptide sequence around phosphorylation site of serine 309 (G-L-S(p)-D-P), according to the protein SYT1.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Zielbeschreibung

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Papa Diogop Ndiaye et al.
Theranostics, 9(3), 661-675 (2019-02-28)
Hypoxic zones are common features of metastatic tumors. Due to inactivation of the von Hippel-Lindau gene (VHL), renal cell carcinomas (RCC) show constitutive stabilization of the alpha subunit of the hypoxia-inducible factor (HIF). Thus, RCC represents a model of chronic
Laura Mercurio et al.
Cell death & disease, 9(11), 1104-1104 (2018-11-01)
IL-36 cytokines, a subgroup of IL-1 family, comprise IL-36α, IL-36β, and IL-36γ agonists, abundantly expressed in psoriatic skin, and IL-36RA and IL-38 antagonists. In psoriatic skin, IL-36 cytokines interfere with keratinocyte cornification programs and induce the release of antimicrobial peptides
Huimin Huang et al.
Toxicology and applied pharmacology, 328, 34-45 (2017-05-16)
Acute liver injury (ALI) is characteristic of abrupt hepatic dysfunction and inflammatory response. Activaion of Kupffer cells (KCs) plays a central role in the pathogenesis of ALI. Since the High Mobility Group A protein2 (HMGA2) occurs as a driver at
Tao Ye et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 41(4), 1584-1595 (2017-03-24)
Dysregulation of ubiquitin-associated protein 2-like (UBAP2L) has been reported in tumors, but its role in hepatocellular carcinoma (HCC) progression is unclear. The expression levels of UBAP2L in HCC tissues and HCC cell lines were detected by western blot and quantitative
Kaili Lian et al.
Oncotarget, 8(30), 48889-48904 (2017-04-08)
TIPE3 (TNFAIP8L3) is the transfer protein of phosphoinositide second messengers that promote cancer. Its role in breast cancer has not been evaluated. We report here that TIPE3 protein was significantly upregulated in human breast cancer tissues as compared with adjacent
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