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Key Documents

SAB4300084

Sigma-Aldrich

Anti-phospho-RPS6KA1 (pThr348) antibody produced in rabbit

affinity isolated antibody

Synonym(e):

Anti-HU-1 antibody produced in rabbit, Anti-MAPKAPK1A antibody produced in rabbit, Anti-RSK antibody produced in rabbit, Anti-RSK1 antibody produced in rabbit, Anti-ribosomal protein S6 kinase, 90kDa, polypeptide 1 antibody produced in rabbit

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About This Item

MDL-Nummer:
MFCD00676462
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

~90 kDa

Speziesreaktivität

mouse, rat, human

Konzentration

1 mg/mL

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

Isotyp

IgG

Immunogene Sequenz

(S-R-TP-P-R)

NCBI-Hinterlegungsnummer

NP_001006666.1

UniProt-Hinterlegungsnummer

Q15418

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

phosphorylation (pThr348)

Angaben zum Gen

human ... RPS6KA1(6195)

Immunogen

Peptide sequence around phosphorylation site of threonine 348 (S-R-T(p)-P-R), according to the protein RPS6KA1.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Zielbeschreibung

Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Rong-Yu Liu et al.
Scientific reports, 10(1), 608-608 (2020-01-19)
Multiple kinases converge on the transcription factor cAMP response element-binding protein (CREB) to enhance the expression of proteins essential for long-term synaptic plasticity and memory. The p90 ribosomal S6 kinase (RSK) is one of these kinases, although its role is
Irem Ozkan-Dagliyan et al.
Cell reports, 31(11), 107764-107764 (2020-06-20)
We address whether combinations with a pan-RAF inhibitor (RAFi) would be effective in KRAS mutant pancreatic ductal adenocarcinoma (PDAC). Chemical library and CRISPR genetic screens identify combinations causing apoptotic anti-tumor activity. The most potent combination, concurrent inhibition of RAF (RAFi)
B Nadratowska-Wesolowska et al.
Oncogene, 33(40), 4823-4836 (2013-10-22)
FGFR1 (fibroblast growth factor receptor 1) regulates many key cellular responses including proliferation, migration and differentiation through activation of signaling pathways. Irregularities in FGFR1 signaling have been implicated in several pathological conditions, including human cancer. In order to discover novel

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