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Key Documents

SAB4300038

Sigma-Aldrich

Anti-phospho-STAT6 (pTyr641) antibody produced in rabbit

affinity isolated antibody

Synonym(e):

Anti-D12S1644 antibody produced in rabbit, Anti-IL-4-STAT antibody produced in rabbit, Anti-STAT6B antibody produced in rabbit, Anti-STAT6C antibody produced in rabbit, Anti-signal transducer and activator of transcription 6, interleukin-4 induced antibody produced in rabbit

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About This Item

MDL-Nummer:
MFCD02097176
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

~110 kDa

Speziesreaktivität

human

Konzentration

1 mg/mL

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

Isotyp

IgG

Immunogene Sequenz

(R-G-YP-V-P)

NCBI-Hinterlegungsnummer

NP_003144.3

UniProt-Hinterlegungsnummer

P42226

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

phosphorylation (pTyr641)

Angaben zum Gen

human ... STAT6(6778)

Immunogen

Peptide sequence around phosphorylation site of tyrosine 641 (R-G-Y(p)-V-P), according to the protein STAT6.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Zielbeschreibung

Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Katherine T Venmar et al.
Cancer research, 74(16), 4329-4340 (2014-06-21)
IL4, a cytokine produced mainly by immune cells, may promote the growth of epithelial tumors by mediating increased proliferation and survival. Here, we show that the type II IL4 receptor (IL4R) is expressed and activated in human breast cancer and
E Yaneth Osorio et al.
PLoS pathogens, 10(6), e1004165-e1004165 (2014-06-27)
Host arginase 1 (arg1) expression is a significant contributor to the pathogenesis of progressive visceral leishmaniasis (VL), a neglected tropical disease caused by the intracellular protozoan Leishmania donovani. Previously we found that parasite-induced arg1 expression in macrophages was dependent on
Sun Hee Jin et al.
Toxicology and applied pharmacology, 280(2), 199-206 (2014-08-30)
Keratinocytes are the major cellular components of human epidermis and play a key role in the modulating cutaneous inflammation and toxic responses. In human chronic skin diseases, the common skin inflammatory phenotypes like skin barrier disruption and epidermal hyperplasia are

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