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Merck

SAB3500340

Sigma-Aldrich

Anti-PTK7 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-CCK-4, Anti-Colon carcinoma kinase-4, Anti-Protein tyrosine Kinase 7

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

rat, mouse, human

Methode(n)

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... PTK7(5754)

Allgemeine Beschreibung

Protein tyrosine kinase-7 (PTK7) is a transmembrane receptor, that belongs to the receptor protein tyrosine kinase (RTKs) family. It has an extracellular immunoglobulin-like domain, a transmembrane domain and an inert tyrosine kinase-like domain. PTK7 is located on human chromosome 6p21.

Immunogen

PTK7 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human PTK7.

Anwendung

Anti-PTK7 antibody has been used in immunohistochemistry.

Biochem./physiol. Wirkung

Protein tyrosine kinase-7 (PTK7) stimulates cell proliferation and invasion. It plays a vital role embryonic development and disease. PTK7 controls radioresistance with the help of nuclear factor-κ B in esophageal squamous cell carcinoma.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Verlinkung

The action of this antibody can be blocked using blocking peptide SBP3500340.

Physikalische Form

Supplied in PBS with 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

PTK7 overexpression in colorectal tumors: Clinicopathological correlation and prognosis relevance.
Tian X, et al.
Oncology Reports, 36(4), 1829-1836 (2016)
PTK7 regulates radioresistance through nuclear factor-kappa B in esophageal squamous cell carcinoma.
Park M, et al.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine, 37(10), 14217-14224 (2016)
PTK7 localization and protein stability is affected by canonical Wnt ligands.
Berger H, et al.
Journal of Cell Science, 130(11), 1890-1903 (2017)
PTK7 is a novel oncogenic target for esophageal squamous cell carcinoma.
Liu K, et al.
World Journal of Surgical Oncology, 15(1), 105-105 (2017)
Ron Chen et al.
Cancer research, 74(10), 2892-2902 (2014-03-22)
Lung cancer remains the most common cause of cancer-related death worldwide and it continues to lack effective treatment. The increasingly large and diverse public databases of lung cancer gene expression constitute a rich source of candidate oncogenic drivers and therapeutic

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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