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Merck

SAB2500066

Sigma-Aldrich

Anti-Aminopeptidase A antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-APA, Anti-ENPEP, Anti-Glutamyl aminopeptidase A, Anti-HGNC:3355, Anti-gp160

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

goat

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

human

Methode(n)

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ENPEP(2028)

Allgemeine Beschreibung

Aminopeptidase A (APA), also known as glutamyl aminopeptidase, is encoded by the gene mapped to human chromosome 4q25. APA is a type II membrane-bound protein. It is expressed in variety of organisms including, animal and plant tissues as well as in bacteria and fungi.

Immunogen

Peptide with sequence C-EQYQKTSLAQEKEK from the internal region of the protein sequence according to NP_001968.2.

Biochem./physiol. Wirkung

Aminopeptidase A (APA) catalyzes the hydrolysis of an N-terminal peptide bond containing N-terminal glutamic acid or aspartic acid. It also plays a vital role in controlling blood pressure in the brain renin-angiotensin system. APA facilitates various processes such as protein maturation, activation, regulation, the degradation of bioactive peptides and in the determination of protein stability.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Amastatin, an inhibitor of aminopeptidase A, produced by actinomycetes.
Aoyagi T
The Journal of Antibiotics, 31(6), 636-638 (1978)
Enzymatic properties of human aminopeptidase A. Regulation of its enzymatic activity by calcium and angiotensin IV.
Goto Y
The Journal of Biological Chemistry, 281(33), 23503-23513 (2006)
L Li et al.
Genomics, 43(3), 380-383 (1997-08-01)
The murine B-lymphocyte differentiation antigen BP-1/6C3 has been identified as glutamyl aminopeptidase (EAP), the gene symbol for which is ENPEP. Using genomic DNA encoding for human EAP as a probe, we identified the ENPEP gene location on human chromosome 4q25

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