SAB1100901

Anti-ARPC4 (26-40) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Synonym(e): Anti-ARC20, Anti-Actin related protein 2/3 complex, subunit 4, Anti-p20-Arc
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: IgG fraction of antiserum
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen ~20 kDa
• Speziesreaktivität: human
• Methode(n): indirect immunofluorescence: suitable; western blot: 1:500-1:2,000
• UniProt-Hinterlegungsnummer: P59998
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... ARPC4(10093)

Beschreibung

Allgemeine Beschreibung

Actin related protein 2/3 complex, subunit 4 (ARPC4) is mapped to human chromosome 3p25.3. It is part of the ARP2/3 complex which connects this complex to the mother filament.

Immunogen

synthetic peptide corresponding to amino acids 26-40 of human ARPC4

Anwendung

Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about us and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

Biochem./physiol. Wirkung

Actin related protein 2/3 complex, subunit 4 (ARPC4) in plants is crucial for action dynamics and cordinates the tip growth and movement. It is highly expressed in most of the pancreatic carcinoma and may regulate cancer cell migration. It interacts with mycobacterial protein Rv1626 and its expression in Mycobacterium tuberculosis impacts its survival and infection profile, making it an effective anti-tuberculosis drug candidate.

Physikalische Form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable