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S4701

Sigma-Aldrich

Suplatast tosylate

≥98% (HPLC)

Synonym(e):

(+/-)-[2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]-ethyl] dimethylsulfonium p-toluenesulfonate, IPD-1151T, ST

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About This Item

Empirische Formel (Hill-System):
C16H26SNO4 · C7H7SO3
CAS-Nummer:
94055-76-2
Molekulargewicht:
499.64
MDL-Nummer:
MFCD00867604
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329824551
NACRES:
NA.77

Qualitätsniveau

100

Assay

≥98% (HPLC)

Form

powder

Farbe

white to off-white

Löslichkeit

DMSO: >20 mg/mL

Lagertemp.

room temp

SMILES String

Cc1ccc(cc1)S([O-])(=O)=O.CCOCC(O)COc2ccc(NC(=O)CC[S+](C)C)cc2

InChI

1S/C16H25NO4S.C7H8O3S/c1-4-20-11-14(18)12-21-15-7-5-13(6-8-15)17-16(19)9-10-22(2)3;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,14,18H,4,9-12H2,1-3H3;2-5H,1H3,(H,8,9,10)

InChIKey

RYVJQEZJUFRANT-UHFFFAOYSA-N

Anwendung

Suplatast tosylate may be used in immune-signaling studies.

Biochem./physiol. Wirkung

Suplatast tosylate is a dimethylsulfonium compound downregulates the expression of histamine H1 receptor gene, suppresses the activity of histidine decarboxylase and regulates IL-4 mRNA. It inhibits the release of histamines and regulates the production of IgE.1,2 Suplatast tosylate is effective in the treatment of mild-to-moderate persistent asthma in children.3
Suplatast tosylate is an anti-allergy, cytokine modulator.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Sandhir B Prasad et al.
The American journal of cardiology, 124(3), 325-333 (2019-06-04)
The inter-relationships between minimal and maximal left atrial volume index (LAVI), left ventricular filling pressures and survival have not been well studied. This study aimed to compare LAVImin with LAVImax with respect to (1) relative prognostic value, and (2) correlation
Vitor Hugo Bezerra et al.
Sensors (Basel, Switzerland), 19(14) (2019-07-25)
Internet of Things (IoT) devices have become increasingly widespread. Despite their potential of improving multiple application domains, these devices have poor security, which can be explored by attackers to build large-scale botnets. In this work, we propose a host-based approach
Robert J Mallis et al.
Journal of biomolecular NMR, 73(6-7), 319-332 (2019-03-01)
Early studies of T cell structural biology using X-ray crystallography, surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC) focused on a picture of the αβT cell receptor (αβTCR) component domains and their cognate ligands (peptides bound to MHC molecules
Juqing Zhang et al.
Applied biochemistry and biotechnology, 189(1), 26-36 (2019-03-13)
Since the birth of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9, the new genome engineering technology has become a hot topic in the scientific community. However, for swine, the system of pig cells' homology directed repair (HDR) is generally unstable
Tien-Chi Hou et al.
OncoTargets and therapy, 12, 6439-6451 (2019-09-10)
This study integrated clinical outcomes and radiomics of advanced thoracic esophageal squamous cell carcinoma patients receiving neoadjuvant concurrent chemoradiotherapy (NACCRT) to establish a novel constraint model for predicting radiation pneumonitis (RP). We conducted a retrospective review for thoracic advanced esophageal
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