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S1439

Sigma-Aldrich

Monoclonal Anti-SERCa2 ATPase antibody produced in mouse

clone IID8

Synonym(e):

Monoclonal Anti-Sarcoplasmic or Endoplasmic Reticulum Ca2+ ATPase

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About This Item

MDL-Nummer:
MFCD00802884
UNSPSC-Code:
12352203
NACRES:
NA.41

Antikörperform

purified from hybridoma cell culture

Qualitätsniveau

200

Antikörper-Produkttyp

primary antibodies

Klon

IID8, monoclonal

Speziesreaktivität

bovine, canine, rat, human, pig, rabbit

Methode(n)

immunocytochemistry: suitable
immunohistochemistry (frozen sections): 1:500
indirect immunofluorescence: suitable
western blot: 1:500-1:5,000

UniProt-Hinterlegungsnummer

P16615

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ATP2A2(488)
rat ... Atp2a2(29693)

Immunogen

purified canine cardiac sarcoplasmic reticulum.

Physikalische Form

Supplied as a solution in PBS containing 0.05% sodium azide.

Sonstige Hinweise

Not suitable for immunoblotting in rat SERCA2.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Haibin Gong et al.
Experimental and therapeutic medicine, 12(3), 1355-1362 (2016-09-08)
The study was conducted to examine the effects of ICI 118,551 on the systolic function of cardiac muscle cells of rats in heart failure and determine the molecular mechanism of selective β2-adrenergic receptor (β2-AR) antagonist on these cells. The chronic
Luca Hegedüs et al.
Frontiers in oncology, 7, 95-95 (2017-06-10)
Several new therapeutic options emerged recently to treat metastatic melanoma; however, the high frequency of intrinsic and acquired resistance among patients shows a need for new therapeutic options. Previously, we identified the plasma membrane Ca2+ ATPase 4b (PMCA4b) as a
Luca Hegedũs et al.
International journal of cancer, 140(12), 2758-2770 (2016-11-05)
Oncogenic mutations of BRAF lead to constitutive ERK activity that supports melanoma cell growth and survival. While Ca2+ signaling is a well-known regulator of tumor progression, the crosstalk between Ca2+ signaling and the Ras-BRAF-MEK-ERK pathway is much less explored. Here
Fernanda M Ferrão et al.
American journal of physiology. Renal physiology, 313(2), F440-F449 (2017-05-05)
ANG II has many biological effects in renal physiology, particularly in Ca2+ handling in the regulation of fluid and solute reabsorption. It involves the systemic endocrine renin-angiotensin system (RAS), but tissue and intracrine ANG II are also known. We have
A O Jorgensen et al.
Cell motility and the cytoskeleton, 9(2), 164-174 (1988-01-01)
Ca2+-ATPase of the sarcoplasmic reticulum was localized in cryostat sections from three different adult canine skeletal muscles (gracilis, extensor carpi radialis, and superficial digitalis flexor) by immunofluorescence labeling with monoclonal antibodies to the Ca2+-ATPase. Type I (slow) myofibers were strongly
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