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RAB0606

Sigma-Aldrich

Human ANGPTL3 / Angiopoietin-related Protein 3 ELISA Kit

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About This Item

UNSPSC-Code:
41116158
NACRES:
NA.32

Speziesreaktivität

human

Verpackung

kit of 96 wells (12 strips x 8 wells)

Methode(n)

ELISA: suitable

Aufnahme

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8.2 pg/mL
standard curve range: 8.19-2000 pg/mL

Nachweisverfahren

colorimetric

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... ANGPTL3(27329)

Allgemeine Beschreibung

Angiopoietin-related protein 3 (ANGPTL3) is a member of the ANGPTL family and is expressed in the liver. The ANGPTL3 gene is mapped on the human chromosome at 1p31.3. Mutations in the ANGPTL3 gene lead to familial combined hypolipidemia, a Mendelian condition that is indicated by lower levels of triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein cholesterol. The ANGPTL3 enzyme-linked immunosorbent assay (ELISA) kit provides for the quantitative measurement of angiopoietin-related protein 3 in cell culture supernatants, plasma, and serum.

Anwendung

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Kit-Komponenten auch einzeln erhältlich

Produkt-Nr.
Beschreibung
SDB
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDB
  • RABSTOP3ELISA Stop Solution (Item I)SDB
  • RABWASH420X Wash Buffer (Item B)SDB

Piktogramme

Corrosion
GHS05

Signalwort

Warning

H-Sätze

H290

P-Sätze

P234 - P390

Gefahreneinstufungen

Met. Corr. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Maria Fernanda Garcés et al.
Scientific reports, 10(1), 21118-21118 (2020-12-05)
This study aimed to determine ANGPTL3 serum levels in healthy young lean and obese non-diabetic men during an oral glucose tolerance test (OGTT) and correlate them with anthropometric, biochemical and hormonal parameters. A case-control study was carried out and 30
Fabiana Quagliarini et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(48), 19751-19756 (2012-11-15)
Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3, a gene located in an intron of DOCK7, results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG). We identified another ANGPTL
Junpeng Ma et al.
Frontiers in oncology, 10, 1382-1382 (2020-09-15)
Meningiomas, as the most common primary tumor of the central nervous system, are known to harbor genomic aberrations that associate with clinical phenotypes. Here we performed genome-wide genotyping for cranial meningiomas in 383 Chinese patients and identified 9,821 copy-number variations
Oleg Kovrov et al.
Journal of lipid research, 60(4), 783-793 (2019-01-29)
Angiopoietin-like (ANGPTL) 8 is a secreted inhibitor of LPL, a key enzyme in plasma triglyceride metabolism. It was previously reported that ANGPTL8 requires another member of the ANGPTL family, ANGPTL3, to act on LPL. ANGPTL3, much like ANGPTL4, is a
Jeremy J Velazquez et al.
Cell systems, 12(1), 41-55 (2020-12-09)
Pluripotent stem cell (PSC)-derived organoids have emerged as novel multicellular models of human tissue development but display immature phenotypes, aberrant tissue fates, and a limited subset of cells. Here, we demonstrate that integrated analysis and engineering of gene regulatory networks

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