RAB0460

Human TGF-β 1 ELISA Kit

for serum, plasma, and cell culture supernatants

• Synonym(e): TGF-beta-1, Transforming growth factor beta-1
• UNSPSC-Code: 41116158
• NACRES: NA.32

Eigenschaften

• Speziesreaktivität: human
• Verpackung: kit of 96 wells (12 strips x 8 wells)
• Methode(n): ELISA: suitable; capture ELISA: suitable
• Aufnahme: sample type serum; sample type cell culture supernatant(s); sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 80 pg/mL; standard curve range: 0.0823-60 ng/mL
• Nachweisverfahren: colorimetric
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... TGFB1(7040)

Beschreibung

Allgemeine Beschreibung

The Human TGF-β 1 ELISA (Enzyme-Linked mmunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human TGF-β 1 in serum, plasma, cell culture supernatants.

Immunogen

Recombinant Human TGF-β 1

Anwendung

For research use only. Not for use in diagnostic procedures.
Human transforming growth factor-β1 (TGF-β1) ELISA Kit has been used to measure level of TGF-β1 released from tubular cells.

Biochem./physiol. Wirkung

Transforming growth factor-β1 (TGF-β1) is a pluripotential cytokine that plays a vital role in the homeostasis of peripheral CD4⁺CD25⁺ regulatory T cells and regulation of FOXP3 (forkhead box P3) expression in vivo. Binding of TGF-β1 to its receptor, activates members of the SMAD protein family involved in gene regulation. Study shows that reduced expression of circulating transforming growth factor-β1 (TGF-β1) might contribute to systemic lupus erythematosus (SLE) development. Polymorphism of TGF-β1 is associated with pathogenesis of rheumatoid arthritis (RA) and pneumoconiosis. Serum TGF-β1 expression is elevated in systemic sclerosis (SSc) patients. Serum TGF-β1 functions as a potential biomarker of Guillain-Barré syndrome (GBS) and SSc.

Sonstige Hinweise

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit-Komponenten auch einzeln erhältlich

• RABELADA ELISA 1X Assay/Sample Diluent Buffer A (Item D1)
• RABELADB ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
• RABSTOP3 ELISA Stop Solution (Item I)
• RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
• RABWASH4 20X Wash Buffer (Item B)

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Warning
• H-Sätze: H290
• P-Sätze: P234 - P390
• Gefahreneinstufungen: Met. Corr. 1
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials