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Merck

R3756

Sigma-Aldrich

Anti-Rat IgG (whole molecule) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.46

Biologische Quelle

rabbit

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

secondary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Methode(n)

indirect ELISA: 1:90,000

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

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Allgemeine Beschreibung

Immunoglobulins (Igs) belongs to the immunoglobulin super-family. There are five different types of Immunoglobulins. Each immunoglobin have two heavy (H) and two light (L) chains held together by disulfide linkages. Each light chain comprises one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region. The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4.

Anwendung

Anti-Rat IgG (whole molecule) antibody produced in rabbit has been used in:
  • ADA immunoassay
  • immunohistochemistry
  • fluorescence-activated cell sorting (FACS)

Biochem./physiol. Wirkung

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

Sonstige Hinweise

Antibody adsorbed with human IgG.

Physikalische Form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Analysenzertifikate (COA)

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The Plant cell, 24(4), 1626-1642 (2012-05-02)
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Hubert Lam et al.
Infection and immunity, 82(9), 3764-3774 (2014-06-25)
Biofilm formation on central lines or peripheral catheters is a serious threat to patient well-being. Contaminated vascular devices can act as a nidus for bloodstream infection and systemic pathogen dissemination. Staphylococcal biofilms are the most common cause of central-line-associated bloodstream
The primate thalamus is a key target for brain dopamine
Sanchez-Gonzalez M, et al.
Journal of neurosciences in rural practice, 25(26), 6076-6083 (2005)
Dopaminergic drug-induced modulation of the expression of the dopamine transporter in peripheral blood lymphocytes in Parkinson?s disease
Fanciulli A, et al.
Pharmacological Reports, 63(4), 1056-1060 (2011)
Universal immunoassay applied during early development of large molecules to understand impact of immunogenicity on biotherapeutic exposure
Bautista AC, et al.
The AAPS Journal, 14(4), 843-849 (2012)

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