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Key Documents

PRS3807

Sigma-Aldrich

Anti-AIM (ab2) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-API6, Anti-Apoptosis inhibitor of macrophages, Anti-CD5 molecule-like, Anti-CD5L, Anti-SPα

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

mouse, human

Methode(n)

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt-Hinterlegungsnummer

O43866

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... CD5L(922)

Immunogen

a 16 amino acid peptide near the amino-terminus of human AIM.

Verlinkung

The action of this antibody can be blocked using blocking peptide SBP3807.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide

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SBP3807

AIM (AB2) Blocking Peptide for PRS3807

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Carlos Alberto Valencia Antúnez et al.
Oncology reports, 32(5), 2093-2103 (2014-09-06)
Carcinogenesis is driven by the accumulation of mutations and abnormal DNA methylation patterns, particularly the hypermethylation of tumor‑suppressor genes. Changes in genomic DNA methylation patterns are established by the DNA methyltransferases (DNMTs) family: DNMT1, DNMT3a and DNMT3b. The DNMTs are
Mina Sasaki et al.
Biochemical and biophysical research communications, 452(3), 622-628 (2014-09-03)
Reactive oxygen species (ROS) can cause severe damage to DNA, proteins and lipids in normal cells, contributing to carcinogenesis and various pathological conditions. While cellular senescence arrests the early phase of cell cycle without any detectable telomere loss or dysfunction.
Ming Li et al.
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 26(4), 371-381 (2014-09-19)
To better understand the contribution of dysregulated DNA methyltransferase 1 (DNMT1) expression to the progression and biology of clear cell renal cell carcinoma (ccRCC). We examined the differences in the expression of DNMT1 in 89 ccRCC and 22 normal tissue
Haiyan Huang et al.
Biochemical and biophysical research communications, 452(3), 708-714 (2014-09-10)
Benzo(a)pyrene (BaP) is a known carcinogen cytotoxic which can trigger extensive cellular responses. Many evidences suggest that inhibitors of poly(ADP-ribose) glycohydrolase (PARG) are potent anticancer drug candidates. However, the role of PARG in BaP carcinogenesis is less understood. Here we
Xiangmei Wu et al.
Molecular neurobiology, 50(3), 839-851 (2014-04-15)
Chronic cerebral hypoperfusion is associated with cognitive decline in aging and age-related neurodegenerative disease. Epigenetic mechanisms are involved in the maintenance of long-term hypoxia-adapted cellular phenotypes. In the present study, the epigenetic signatures such as DNA methylation and histone acetylation
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