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Key Documents

PRS2283

Sigma-Aldrich

Anti-RIP3 antibody produced in rabbit

affinity isolated antibody

Synonym(e):

Anti-Receptor-Interacting serine-threonine kinase 3

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About This Item

MDL-Nummer:
MFCD03097232
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Mol-Gew.

predicted mol wt 57 kDa

Speziesreaktivität

rat, human, mouse

Methode(n)

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt-Hinterlegungsnummer

Q9QZL0

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

mouse ... Ripk3(56532)

Verwandte Kategorien

Immunogen

a peptide corresponding to amino acids 473-486 of murine RIP3.

Anwendung

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)

Verlinkung

The action of this antibody can be blocked using blocking peptide SBP2283.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Ähnliches Produkt

Produkt-Nr.
Beschreibung
Preisangaben

SBP2283

RIP3 Blocking Peptide for PRS2283

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Douglas Ruhl et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(15), 2951-2964 (2019-02-09)
Ototoxic side effects of cisplatin and aminoglycosides have been extensively studied, but no therapy is available to date. Sensory hair cells, upon exposure to cisplatin or aminoglycosides, undergo apoptotic and necrotic cell death. Blocking these cell death pathways has therapeutic
Imene Jaadane et al.
Scientific reports, 10(1), 6733-6733 (2020-04-23)
Exposure Limit Values (ELV) for artificial lighting were defined in order to prevent light-induced damage to the retina. The evaluation of the lighting devices include the correction of their spectra by the B(λ) function or blue light hazard function, representing
Mi Wang et al.
Journal of anatomy, 237(1), 29-47 (2020-03-13)
Receptor-interacting protein 3 (RIP3) plays an important role in the necroptosis signaling pathway. Our previous studies have shown that the RIP3/mixed lineage kinase domain-like protein (MLKL)-mediated necroptosis occurs in retinal ganglion cell line 5 (RGC-5) following oxygen-glucose deprivation (OGD). However
Xia-Lian Wu et al.
Nature communications, 12(1), 1627-1627 (2021-03-14)
RIPK3 amyloid complex plays crucial roles during TNF-induced necroptosis and in response to immune defense in both human and mouse. Here, we have structurally characterized mouse RIPK3 homogeneous self-assembly using solid-state NMR, revealing a well-ordered N-shaped amyloid core structure featured
Johaiber Fuchslocher Chico et al.
Oncotarget, 9(16), 12941-12958 (2018-03-22)
The disintegrin metalloprotease ADAM17 has a critical role in intestinal inflammation and regeneration in mice, as illustrated by the dramatically increased susceptibility of ADAM17 hypomorphic (ADAM17ex/ex) mice to dextran sulfate sodium (DSS)-induced colitis. Similarly, necroptosis has been implicated in inflammatory
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