PLA0054

Goat anti-Chk1 Antibody, Affinity Purified

• Synonym(e): 1, CHK1, CHK1 (checkpoint; S.pombe) homolog, CHK1 checkpoint homolog, CHK1 checkpoint homolog (S. pombe), Checkpoint, Chk1-S, S. pombe, cell cycle checkpoint kinase, checkpoint kinase-1, homolog of
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: goat
• Qualitätsniveau: 100
• Antikörperform: affinity purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Speziesreaktivität: human
• Methode(n): western blot: 1:2,500- 1:15,000
• Hinterlegungsnummer: NP_001265.1
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Angaben zum Gen: goat ... Chk1(1111)

Beschreibung

Immunogen

The epitope recognized by PLA0054 maps to a region between residues 200 and 250 of human Checkpoint Kinase 1 using the numbering given in entry NP_001265.1 (GeneID 1111).

Physikalische Form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Sonstige Hinweise

Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable