PENNA

Penicillin G Natriumsalz

~1650 U/mg

• Synonym(e): Benzylpenicillin Natriumsalz
• Empirische Formel (Hill-System): C₁₆H₁₇N₂NaO₄S
• CAS-Nummer: 69-57-8
• Molekulargewicht: 356.37
• Beilstein: 3834217
• EG-Nummer: 200-710-2
• MDL-Nummer: MFCD00069666
• UNSPSC-Code: 51283424
• PubChem Substanz-ID: 24899068
• NACRES: NA.85

Eigenschaften

• Form: powder
• Spezifische Aktivität: ~1650 U/mg
• Löslichkeit: H₂O: 100 mg/mL
• Wirkungsspektrum von Antibiotika: Gram-negative bacteria; Gram-positive bacteria
• Wirkungsweise: cell wall synthesis | interferes
• Lagertemp.: 2-8°C
• SMILES String: [Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O
• InChI: 1S/C16H18N2O4S.Na/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
• InChIKey: FCPVYOBCFFNJFS-LQDWTQKMSA-M

Beschreibung

Allgemeine Beschreibung

Penicillin G is a narrow spectrum antibiotic. It is effective against Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G contains β-lactam ring in their chemical structure.

Anwendung

Penicillin G sodium salt has been used:

• to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility
• in cell culture alone as well as in combination with streptomycin and other antibiotics
• to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining

Biochem./physiol. Wirkung

Wirkungsweise: Inhibiert die Synthese von Bakterienzellwänden.
Antimicrobielles Spektrum: Gram-positive Bakterien..

Verpackung

1mu,10mu,100mu

Vorsicht

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H₂O at 100 mg/mL.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place.Product contains Penicillin

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H317
• P-Sätze: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Gefahreneinstufungen: Skin Sens. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves