P8087

Monoclonal Anti-Plakoglobin (Catenin γ) antibody produced in mouse

clone 15F11, ascites fluid, buffered aqueous solution

• MDL-Nummer: MFCD00164716
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 200
• Konjugat: unconjugated
• Antikörperform: ascites fluid
• Antikörper-Produkttyp: primary antibodies
• Klon: 15F11, monoclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 85 kDa
• Enthält: 15 mM sodium azide
• Speziesreaktivität: bovine, canine, human
• Methode(n): immunocytochemistry: suitable using cultured cells; immunohistochemistry (frozen sections): suitable; immunoprecipitation (IP): suitable; indirect immunofluorescence: 1:1,000 using cultured MDBK cells; microarray: suitable; western blot: 1:2,000 using cultured MDBK cells
• Isotyp: IgG1
• UniProt-Hinterlegungsnummer: P14923
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... JUP(3728)

Beschreibung

Allgemeine Beschreibung

Plakoglobin is a desmosomal protein that regulates developmental signalling in vertebrates. Tyrosine phosphorylation of plakoglobin has been linked to adenocarcinomas . Plakoglobin may function as a tumor suppressor in ovarian and breast cancers .

Spezifität

The antibody recognizes the plakoglobin (catenin-γ) molecule (85 kDa and possibly a slightly lower band) by immunoblotting. It does not cross-react with β-catenin. The antibody reacts with plakoglobin in bovines, humans and dogs, but does not react with β catenin.

Immunogen

recombinant chicken plakoglobin.

Anwendung

Monoclonal anti-plakoglobin (catenin γ) antibody is suitable for use in immunocytochemistry (using MDCK cells), immunoprecipitation, and in immunoblotting . The antibody may also be used for immunohistochemistry (frozen sections), microarray, western blot (1:500, using cultured MDBK cells) and indirect immunofluorescence (1:1000, using cultured MDBK cells).

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable