Direkt zum Inhalt
Merck
Alle Fotos(4)

Dokumente

P4562

Sigma-Aldrich

Natriumpyruvat

powder, BioXtra, suitable for mouse embryo cell culture

Synonym(e):

α-Ketopropionsäure Natriumsalz, 2-Oxopropionsäure Natriumsalz, Brenztraubensäure Natriumsalz, Pyruvat Natrium

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(4)

About This Item

Lineare Formel:
CH3COCOONa
CAS-Nummer:
113-24-6
Molekulargewicht:
110.04
Beilstein:
3568341
EG-Nummer:
204-024-4
MDL-Nummer:
MFCD00002586
UNSPSC-Code:
12352207
PubChem Substanz-ID:
24898552
NACRES:
NA.75

Produktlinie

BioXtra

Qualitätsniveau

200

Assay

≥99%

Form

powder

Methode(n)

cell culture | embryo: suitable

mp (Schmelzpunkt)

>300 °C (lit.)

Löslichkeit

H2O: 100 mg/mL

Lagertemp.

2-8°C

SMILES String

[Na+].CC(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

InChIKey

DAEPDZWVDSPTHF-UHFFFAOYSA-M

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Verwandte Kategorien

Allgemeine Beschreibung

Pyruvate, the end-product of the glycolysis pathway, is the anion of pyruvic acid.

Anwendung

Sodium pyruvate has been used:
  • as a supplement in Ca2+ + N-Tris(hydroxymethil)methyl-2-aminoethanesulfonic acid (TES)–NaCl medium for sperm incubation
  • as a supplement in TCM-199 hepes modification solution for cumulus-oocytes complexes (COC′s) culture
  • as a supplement in Dulbecco′s modified Eagle medium (DMEM) to culture mouse primary hepatocytes (MPHs) and also to intraperitoneally inject fasted mice for glucose production assessment

Biochem./physiol. Wirkung

Sodium pyruvate is mainly used as a constituent in culture broth and media. It exhibits anti-oxidation and anti-inflammatory properties. Hence sodium pyruvate is considered a possible therapy for allergic rhinitis. Sodium pyruvate might also be a new approach treating lactic acidosis.
Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. Sodium pyruvate attenuates oxidative stress in vitro. The 100 mM solution should be diluted at 1:100 for most cell culture applications. This product has been qualified for use in mouse embryo cultures.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H317 - H319

Gefahreneinstufungen

Eye Irrit. 2 - Skin Sens. 1B

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Jing Yang et al.
Artificial cells, nanomedicine, and biotechnology, 44(1), 48-55 (2014-04-05)
To examine the effects of sodium pyruvate (SP) on metabolic acidosis. For the in vivo experiments, we evaluated effects of SP on an ammonium chloride (NH4Cl)-induced hyperchloremic acidosis rat model. SP was infused at overall doses of 2, 4, and
Maheul Ploton et al.
Journal of hepatology, 69(5), 1099-1109 (2018-07-08)
Embedded into a complex signaling network that coordinates glucose uptake, usage and production, the nuclear bile acid receptor FXR is expressed in several glucose-processing organs including the liver. Hepatic gluconeogenesis is controlled through allosteric regulation of gluconeogenic enzymes and by
Rekin's Janky et al.
PLoS computational biology, 10(7), e1003731-e1003731 (2014-07-25)
Identifying master regulators of biological processes and mapping their downstream gene networks are key challenges in systems biology. We developed a computational method, called iRegulon, to reverse-engineer the transcriptional regulatory network underlying a co-expressed gene set using cis-regulatory sequence analysis.
Lotta Tengroth et al.
PloS one, 9(6), e98239-e98239 (2014-06-03)
The human nasal epithelium is an important physical barrier, and a part of the innate immune defense that protect against pathogens. The epithelial cells recognize microbial components by pattern-recognition receptors (PRRs), and thereby trigger an immune response. Even though TLR3
Yoh Arita et al.
Nature communications, 5, 4552-4552 (2014-07-30)
The origin and developmental mechanisms underlying coronary vessels are not fully elucidated. Here we show that myocardium-derived angiopoietin-1 (Ang1) is essential for coronary vein formation in the developing heart. Cardiomyocyte-specific Ang1 deletion results in defective formation of the subepicardial coronary
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.