P1743

Protein Phosphatase 2C from bovine brain

buffered aqueous glycerol solution

• CAS-Nummer: 362690-38-8
• MDL-Nummer: MFCD04041076
• UNSPSC-Code: 12352200
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: bovine brain
• Qualitätsniveau: 200
• Assay: >90% (SDS-GE)
• Form: buffered aqueous glycerol solution
• Spezifische Aktivität: ~1000 units/mg protein
• Mol-Gew.: 42-45 kDa
• Verpackung: vial of 1 μg
• Methode(n): ligand binding assay: suitable
• UniProt-Hinterlegungsnummer: P67774
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: bovine ... PPP2CA(282320)

Beschreibung

Allgemeine Beschreibung

Protein phosphatase 2C (PP2C) is a member of protein phosphatases, Mg²⁺/Mn²⁺ dependent (PPM) family. PP2C is a monomeric enzymes found in both prokaryotes and eukaryotes.

Biochem./physiol. Wirkung

In Arabidopsis, protein phosphatase 2C (PP2C) negatively regulates plant hormone, abscisic acid (ABA) signal transduction. In eukaryotes, this protein modulates the cell cycle by reversing the activating phosphorylation of cyclin-dependent protein kinases (CDKs). PP2C acts as a crucial physiological regulators of cell growth and of cellular stress signaling.

Einheitendefinition

One unit will release 1.0 nanomole of phosphate from ³²P-labeled myelin basic protein at pH 7.0 at 30 °C

Physikalische Form

Solution in 50 mM Tris-HCl, pH 7.0, containing 14 mM 2-mercaptoethanol, 1 mM benzamidine, 0.1 mM PMSF, 1 mM EDTA, and 50% glycerol

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H317
• P-Sätze: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Gefahreneinstufungen: Skin Sens. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable