O003

β-Funaltrexamine hydrochloride

solid

• Synonym(e): β-FNA hydrochloride, (E)-4-[[(5α,6β)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]amino]-4-oxo-2-butenoic acid methyl ester hydrochloride
• Empirische Formel (Hill-System): C₂₅H₃₀N₂O₆ · HCl
• CAS-Nummer: 72786-10-8
• Molekulargewicht: 490.98
• MDL-Nummer: MFCD10565941
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 24897921
• NACRES: NA.77

Eigenschaften

• Form: solid
• Qualitätsniveau: 100
• Arzneimittelkontrolle: regulated under CDSA - not available from Sigma-Aldrich Canada
• Lagerbedingungen: desiccated
• Farbe: white
• Löslichkeit: H₂O: 7.5 mg/mL (aqueous solutions should be promptly used); methanol: 7.6 mg/mL (do not store in ethanolic solution; methanolic solutions may be stored for several weeks at 4 °C)
• Lagertemp.: −20°C
• SMILES String: Cl.COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5OC1[C@]2(CCN3CC6CC6)c45
• InChI: 1S/C25H30N2O6.ClH/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14;/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29);1H/b7-6+;/t16-,18-,23+,24+,25-;/m1./s1
• InChIKey: BIPHUOBUKMPSQR-NQGXHZAGSA-N

Beschreibung

Biochem./physiol. Wirkung

Selective irreversible μ opioid receptor antagonist that is also a κ opioid receptor agonist.

Leistungsmerkmale und Vorteile

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)