N9412

6β-Naltrexol hydrate

≥96% (HPLC), powder

• Synonym(e): (5α,6β)-17-(Cyclopropylmethyl)-4,5-epoxy-morphinan-3,6,14-triol hydrate
• Empirische Formel (Hill-System): C₂₀H₂₅NO₄ · xH₂O
• CAS-Nummer: 1034528-53-4
• Molekulargewicht: 343.42 (anhydrous basis)
• MDL-Nummer: MFCD08277038
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24724560
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥96% (HPLC)
• Form: powder
• Arzneimittelkontrolle: regulated under CDSA - not available from Sigma-Aldrich Canada
• Farbe: white
• Löslichkeit: DMSO: ~12 mg/mL; H₂O: insoluble
• Lagertemp.: 2-8°C
• SMILES String: [H]O[H].O[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC6CC6)c45
• InChI: 1S/C20H25NO4.H2O/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11;/h3-4,11,14-15,18,22-24H,1-2,5-10H2;1H2/t14-,15-,18+,19+,20-;/m1./s1
• InChIKey: VHGGWFVHXKTOPK-CDHBEYIESA-N

Beschreibung

Biochem./physiol. Wirkung

Neutral antagonist of the μ-opioid receptor. A reduction of withdrawal effects associated with neutral μ-opioid receptor antagonists may offer advantages in treating opioid overdose and addiction.

Leistungsmerkmale und Vorteile

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)