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Merck

M1555

Sigma-Aldrich

MAHMA NONOate

Synonym(e):

6-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-hexanamine, NOC-9

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About This Item

Empirische Formel (Hill-System):
C8H20N4O2
CAS-Nummer:
Molekulargewicht:
204.27
MDL-Nummer:
UNSPSC-Code:
12352106
PubChem Substanz-ID:
NACRES:
NA.25

Qualitätsniveau

Versandbedingung

dry ice

Lagertemp.

−70°C

SMILES String

[H][N+]([H])(C)CCCCCCN(C)N([O-])N=O

InChI

1S/C8H19N4O2/c1-9-7-5-3-4-6-8-11(2)12(14)10-13/h9H,3-8H2,1-2H3/q-1/p+1

InChIKey

WASRCWNCCFPNEJ-UHFFFAOYSA-O

Anwendung

NO donor

Biochem./physiol. Wirkung

NO release: t1/2 = 3 min (phosphate buffer at 22° C)

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Philip E James et al.
Circulation research, 94(7), 976-983 (2004-02-14)
Vascular dysfunction in diabetes is attributed to lack of bioavailable nitric oxide (NO) and is postulated as a primary cause of small vessel complications as a result of poor glycemic control. Although it has been proposed that NO is bound
D Clark et al.
Molecular plant-microbe interactions : MPMI, 13(12), 1380-1384 (2000-12-06)
We used a variety of nitric oxide (NO) donors to demonstrate that NO inhibits the activities of tobacco catalase and ascorbate peroxidase (APX). This inhibition appears to be reversible because removal of the NO donor led to a significant recovery
Stefan Muenster et al.
Anesthesiology, 125(5), 952-963 (2016-10-19)
Transfusion of packed erythrocytes stored for a long duration is associated with increased pulmonary arterial pressure and vascular resistance. Prolonged storage decreases erythrocyte deformability, and older erythrocytes are rapidly removed from the circulation after transfusion. The authors studied whether treating
H P Monteiro et al.
Free radical biology & medicine, 28(2), 174-182 (2001-04-03)
Nitric oxide (NO) can participate in cellular signaling. In this study, monoclonal antibodies against proteins from the growth factor-mediated signalling pathway were used to identify a set of 126-, 56-, 43-, and 40-kDa proteins phosphorylated on tyrosine at NO stimulation
S H Lin et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 20(9), 1380-1391 (2000-09-20)
Neuronal injury may be dependent upon the generation of the free radical nitric oxide (NO) and the subsequent induction of programmed cell death (PCD). Although the nature of this injury may be both preventable and reversible, the underlying mechanisms that

Artikel

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

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