L8045

Liquiritin

from Glycyrrhizae root (licorice root), ≥98% (HPLC)

• Synonym(e): 4′,7-Dihydroxyflavanon-4′-glucosid, Liquiritosid
• Empirische Formel (Hill-System): C₂₁H₂₂O₉
• CAS-Nummer: 551-15-5
• Molekulargewicht: 418.39
• MDL-Nummer: MFCD00210526
• UNSPSC-Code: 12352200
• NACRES: NA.25

Eigenschaften

• Biologische Quelle: Glycyrrhizae root (licorice root)
• Assay: ≥98% (HPLC)
• Form: powder
• Anwendung(en): metabolomics; vitamins, nutraceuticals, and natural products
• Lagertemp.: 2-8°C
• SMILES String: O=C1C2=CC=C(O)C=C2O[C@H](C3=CC=C(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C=C3)C1
• InChI: 1S/C21H22O9/c22-9-17-18(25)19(26)20(27)21(30-17)28-12-4-1-10(2-5-12)15-8-14(24)13-6-3-11(23)7-16(13)29-15/h1-7,15,17-23,25-27H,8-9H2/t15-,17+,18+,19-,20+,21+/m0/s1
• InChIKey: DEMKZLAVQYISIA-ZRWXNEIDSA-N

Beschreibung

Allgemeine Beschreibung

Liquiritin is a type of flavone, present as an active ingredient in Glycyrrhiza uralensis and Glycyrrhiza glabra extract. It is a constituent of many traditional Chinese medicine formulas popularly used as a cure for asthma, peptic ulcers, and cough.

Anwendung

Liquiritin has been used to analyze the extract of Glycyrrhiza uralensis and examine its components for anti-Hepatitis C virus activity.

Biochem./physiol. Wirkung

Liquiritin has been attributed to show antidepressant-like and antioxidant activity. It causes apoptosis in cell lines having gastric cancer and promyelocytic leukemia. Liquiritin also demonstrates neurotrophic effects and hence has been considered as a potential contender for the management of different neurodegenerative diseases. It shows an anti-inflammatory property with protection to the liver against oxidative damage. It has depigmenting ability and is a potential medicine for melasma.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable