I9659

Monoclonal Anti-Insulin-like Growth Factor-II antibody produced in mouse

clone 75014, purified immunoglobulin, lyophilized powder

• Synonym(e): Anti-IGF2, Anti-INSIGF
• MDL-Nummer: MFCD00162567
• UNSPSC-Code: 51111800
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: 75014, monoclonal
• Form: lyophilized powder
• Speziesreaktivität: human
• Methode(n): western blot: 1-2 μg/mL
• Isotyp: IgG2a
• UniProt-Hinterlegungsnummer: P01344
• Lagertemp.: −20°C
• Angaben zum Gen: human ... IGF2(3481)

Beschreibung

Immunogen

purified, E. coli-derived recombinant human insulin-like growth factor-II.

Biochem./physiol. Wirkung

Insulin-like growth factors -I and -II are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -II (IGF-II) is widely expressed during embryonic stages and regulates the placental development. IGF-II acts via specific receptor, IGF-IIR, the binding does not result in signal transduction, but is a mechanism to restrict the bioavailability of IGF-II. The effects of IGF-II signaling are important in growth of blood vessels (angiogenesis) gene transcription, proliferation and transformation.

Physikalische Form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)