H8892

Heparin-disaccharid I-H Natriumsalz

• Synonym(e): α-ΔUA-2S-[1→4]-GlcN-6S
• Lineare Formel: C₁₂H₁₇NO₁₆S₂Na₂
• CAS-Nummer: 136098-04-9
• Molekulargewicht: 541.37
• MDL-Nummer: MFCD00466926
• UNSPSC-Code: 12352201
• PubChem Substanz-ID: 329815254
• NACRES: NA.25

Eigenschaften

• Assay: ~99% (HPLC)
• Form: solid
• Methode(n): HPLC: suitable
• Farbe: white to faint yellow
• Lagertemp.: −20°C
• SMILES String: [Na+].[Na+].[Na+].N[C@H]1C(O)O[C@H](COS([O-])(=O)=O)[C@@H](O[C@@H]2OC(=C[C@H](O)[C@H]2OS([O-])(=O)=O)C([O-])=O)[C@@H]1O
• InChI: 1S/C12H19NO16S2.3Na/c13-6-7(15)9(5(26-11(6)18)2-25-30(19,20)21)28-12-8(29-31(22,23)24)3(14)1-4(27-12)10(16)17;;;/h1,3,5-9,11-12,14-15,18H,2,13H2,(H,16,17)(H,19,20,21)(H,22,23,24);;;/q;3*+1/p-3/t3-,5+,6+,7+,8+,9+,11?,12-;;;/m0.../s1
• InChIKey: WHYGSGRAJJCXLY-LXROVJCJSA-K

Beschreibung

Anwendung

Heparin disaccharide I-H sodium salt has been used as a non-naphthalene, negatively charged, bivalent compound to test its ability to induce liquid-liquid phase separation (LLPS).

Biochem./physiol. Wirkung

Heparin disaccharide is a bivalent compound with less hydrophobic nature. It elevates the cytosolic calcium (Ca²⁺) extrusion rate and may serve as a potential drug for the activation of Na+ /Ca²⁺ exchanger (NCX).

Products of the digestion of heparin and heparan sulfate by various heparinases

Sonstige Hinweise

In the following listings, ΔUA = 4-deoxy-L-threo-hex-4-enopyranosyluronic acid; GlcN = D-glucosamine; Ac = Acetyl; NS, 2S, 6S, = N-sulfo, 2-sulfate and 6-sulfate respectively.

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)