H7250

Histamin -dihydrochlorid

≥99% (TLC), powder, endogenous histamine receptor agonist

• Synonym(e): 2-(4-Imidazolyl)-ethylamin -dihydrochlorid
• Empirische Formel (Hill-System): C₅H₉N₃ · 2HCl
• CAS-Nummer: 56-92-8
• Molekulargewicht: 184.07
• Beilstein: 3624116
• EG-Nummer: 200-298-4
• MDL-Nummer: MFCD00012703
• UNSPSC-Code: 12352116
• eCl@ss: 32160406
• PubChem Substanz-ID: 24277777
• NACRES: NA.77

Eigenschaften

• product name: Histamin -dihydrochlorid, ≥99% (TLC), powder
• Assay: ≥99% (TLC)
• Form: powder
• Farbe: white to off-white
• mp (Schmelzpunkt): 249-252 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: Cl[H].Cl[H].NCCc1c[nH]cn1
• InChI: 1S/C5H9N3.2ClH/c6-2-1-5-3-7-4-8-5;;/h3-4H,1-2,6H2,(H,7,8);2*1H
• InChIKey: PPZMYIBUHIPZOS-UHFFFAOYSA-N
• Angaben zum Gen: human ... HRH1(3269) , HRH2(3274)

Beschreibung

Allgemeine Beschreibung

Histamine dihydrochloride is a derivative of histamine. It prevents the formation of ROS (reactive oxygen species), which inhibits the activation of T cells and natural killer cells. Histamine dihydrochloride is implicated in tumor cell apoptosis. It prevents the relapse of acute myeloid leukemia in patients.

Anwendung

Histamine dihydrochloride has been used:

• as a orthograde cotransmitter in producing excitatory postsynaptic potential (EPSP)
• to determine its level in fish using HPLC (high performance liquid chromatography)
• to assess the tracheal response to antigens in guinea-pigs

Leistungsmerkmale und Vorteile

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H315,H317,H319,H334,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves