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Merck

GW21017

Sigma-Aldrich

Anti-Tenascin antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-Cytotactin, Anti-Neuronectin, Anti-Tenascin C (hexabrachion)

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

chicken

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

human

Hersteller/Markenname

Genway 15-288-21017

Methode(n)

western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... TNC(3371)

Immunogen

Immunogen Sequence: GI # 4504549, sequence 18-175
Recombinant tenascin C (hexabrachion)

Anwendung

Anti-Tenascin antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. It is also used for immunohistology.

Biochem./physiol. Wirkung

Tenascin-C (TNC) is an extracellular matrix protein that is expressed at low levels in normal adult tissue but is highly expressed around many tumors including ovarian tumors. High levels are observed in many diseases like heart failure, thrombosis, atherosclerosis and cancer. It plays an indispensable role in tumor development. Expression of this gene is induced by growth factors as well as mechanical strain in fibroblast. It is up-regulated within glioma tissues and cultured glioma cell lines. TNC possesses a multi-modular structure with a variety of functional properties.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Yucal Wang et al.
Oncology research, 20(11), 509-516 (2013-09-26)
Osteosarcoma (OS) is a kind of malignancy wherein the tumor cells form malignant bone-like or bone tissue. Tenascin-C (TN-C), an important extracellular matrix (ECM) protein, plays an indispensable role in tumor development. However, its regulatory factors, expression, and function in
Nicole Brösicke et al.
Cell and tissue research, 354(2), 409-430 (2013-08-22)
The extracellular matrix (ECM) protein tenascin-C (TN-C) is upregulated within glioma tissues and cultured glioma cell lines. TN-C possesses a multi-modular structure and a variety of functional properties have been reported for its domains. We describe five novel monoclonal antibodies
D Tastekin et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(7), 6619-6625 (2014-04-04)
Tenascin-C (TNC) is a key molecule in tissue remodeling, and high levels are observed in many diseases, including heart failure, thrombosis, atherosclerosis, and cancer. High TNC expression by immunohistochemical analysis has been shown in invasive and metastasizing tissues from a
Tastekin Didem et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(7), 6777-6782 (2014-04-12)
Tenascin-C (TNC) is an extracellular matrix protein that is expressed at low levels in normal adult tissue but is highly expressed around many tumors including ovarian tumors. The objective of this study was to determine the clinical significance of the
Daniel J Gibson et al.
Investigative ophthalmology & visual science, 54(7), 4776-4781 (2013-06-27)
To determine the topographical location and time course of development of corneal haze in a phototherapeutic keratectomy model using slit lamp examination, macrophotography, quantitative image analysis, and immunofluorescence staining of corneal sections. Rabbit corneas were ablated with an excimer laser

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