F0504

Folatbindendes Protein aus Kuhmilch

lyophilized powder

• MDL-Nummer: MFCD00131098
• UNSPSC-Code: 12352202
• NACRES: NA.61

Eigenschaften

• Biologische Quelle: bovine milk
• Qualitätsniveau: 200
• Form: lyophilized powder
• Verwendung: mg sufficient for ~4,000 assays
• Zusammensetzung: Protein, 20-40% modified Warburg-Christian
• Methode(n): ligand binding assay: suitable; surface plasmon resonance (SPR): suitable
• Kapazität: 1.5-6.0 μg/mg, protein binding capacity (folic acid)(25 °C at pH 7.5.)
• Lagertemp.: −20°C

Beschreibung

Anwendung

Folate binding protein can be used in radioligand binding assays of serum folate. The folate receptor has been used in studies as a therapeutic target in a variety of cancers.

Folate binding protein from bovine milk has been used in folate binding studies using surface plasmon resonance and in the uptake studies in kidney proximal tubule cells.

Useful for radioligand binding assays of serum folate. May also bind N-methyltetrahydrofolic acid and other folate analogues.

Biochem./physiol. Wirkung

Folate-binding protein (FBP) is present as a cell receptor and binds to folate in equimolar ratio. It is involved in the transport of folate and improves their bioavailability.

Verpackung

Package size based on protein content

Qualität

Purified over 1,000 fold. May contain a trace of β-mercaptoethanol.

Physikalische Form

Lyophilized powder containing buffer salt as sodium citrate

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)