D9286

Paraoxon-Ethyl

≥90%, oil

• Synonym(e): O,O-Diethyl O-(4-nitrophenyl)-phosphat, Diethyl-p-nitrophenylphosphat, Paraoxon, Paraoxon-ethyl
• Lineare Formel: O₂NC₆H₄OP(O)(OC₂H₅)₂
• CAS-Nummer: 311-45-5
• Molekulargewicht: 275.20
• Beilstein: 1915526
• EG-Nummer: 206-221-0
• MDL-Nummer: MFCD00007316
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 24894279
• NACRES: NA.77

Eigenschaften

• Assay: ≥90%
• Form: oil
• Farbe: yellow
• Brechungsindex: n20/D 1.51 (lit.)
• Dichte: 1.274 g/mL at 25 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3
• InChIKey: WYMSBXTXOHUIGT-UHFFFAOYSA-N
• Angaben zum Gen: human ... PON1(5444)

Beschreibung

Anwendung

Paraoxon-ethyl has been used as a substrate in paraoxonase (PON) activity assay. It has also been used as a lipase inhibitor to study the effects of anacetrapib on homotypic transfer from high density lipoprotein L3 (HDL3) to HDL2 in vivo.

Biochem./physiol. Wirkung

Potenter irreversibler Acetylcholinesterase-Inhibitor

Vorsicht

air sensitive: handle under argon

Physikalische Form

Oily liquid

Sicherheitshinweise

• Piktogramme: GHS06,GHS09
• Signalwort: Danger
• H-Sätze: H300 + H310,H410
• P-Sätze: P262 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P310
• Gefahreneinstufungen: Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter