C6594

Anti-c-Myc

clone 9E10, purified immunoglobulin, buffered aqueous solution

• Synonym(e): Anti-c-Myc
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Konjugat: CY3 conjugate
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: 9E10, monoclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Methode(n): direct immunofluorescence: 1:50 using formalin-fixed, paraffin-embedded human colon carcinoma tissue
• UniProt-Hinterlegungsnummer: P01106
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... MYC(4609)

Beschreibung

Allgemeine Beschreibung

Monoclonal Anti-c-myc (mouse IgG1 isotype) is derived from the 9E10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized BALB/c mouse. The c-Myc gene encodes a polypeptide with a predicted molecular weight of 49 kDa.

Immunogen

Synthetisches Peptid des menschlichen p62^c-Myc-Proteins.

Anwendung

Monoclonal Anti-c-MycCy3^™ antibody produced in mouse has been used in:

• western blotting
• immunocytochemistry
• Immunofluorescence

Biochem./physiol. Wirkung

The encoded protein is involved in cell proliferation, growth and apoptosis. The c-myc gene has been implicated in the development of a number of neoplasms in a variety of avian and mammalian species. The human c-myc protooncogene is the cellular homolog of the avian v-myc gene found in several leukemogenic retroviruses. Increased expression of the cellular oncogene c-myc has been described in a variety of human tumors, occurring by several different mechanisms, including gene amplification and chromosomal translocation.

Physikalische Form

Solution in 0.01 M sodium phosphate buffered saline containing 1% bovine serum albumin and 15 mM sodium azide.

Rechtliche Hinweise

Cy3 is a trademark of Cytiva

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)