C1355

Z-Leu-Glu(O-Me)-His-Asp(O-Me) fluoromethyl ketone trifluoroacetate salt hydrate

≥90%

• Synonym(e): Z-LEHD-FMK, Z-LE(OMe)HD(OMe)-FMK
• Empirische Formel (Hill-System): C₃₂H₄₃FN₆O₁₀ · xC₂HF₃O₂ · yH₂O
• CAS-Nummer: 210345-04-3
• Molekulargewicht: 690.72 (anhydrous free base basis)
• MDL-Nummer: MFCD01862609
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329774878

Eigenschaften

• Assay: ≥90%
• Form: film
• Lagerbedingungen: desiccated
• Farbe: colorless to light brown
• Löslichkeit: DMSO: 10 mg/mL, clear
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: COC(=O)CC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@@H](CC(=O)OC)C(=O)CF
• InChI: 1S/C32H43FN6O10/c1-19(2)12-24(39-32(46)49-17-20-8-6-5-7-9-20)30(44)36-22(10-11-27(41)47-3)29(43)38-25(13-21-16-34-18-35-21)31(45)37-23(26(40)15-33)14-28(42)48-4/h5-9,16,18-19,22-25H,10-15,17H2,1-4H3,(H,34,35)(H,36,44)(H,37,45)(H,38,43)(H,39,46)/t22-,23-,24-,25-/m0/s1
• InChIKey: YXRKBEPGVHOXSV-QORCZRPOSA-N

Beschreibung

Anwendung

A cell-permeable inhibitor of caspase-9, which exhibits competitive and irreversible inhibition.

Leistungsmerkmale und Vorteile

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.