B1552

Bromoenol lactone

≥98% (TLC)

• Synonym(e): BEL, E-6-(Bromoethylene)tetrahydro-3-(1-naphthyl)-2H-pyran-2-one
• Empirische Formel (Hill-System): C₁₆H₁₃BrO₂
• CAS-Nummer: 88070-98-8
• Molekulargewicht: 317.18
• MDL-Nummer: MFCD00270871
• UNSPSC-Code: 41106300
• PubChem Substanz-ID: 24278257
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Qualitätsniveau: 200
• Assay: ≥98% (TLC)
• Form: powder
• Wirksamkeit: 636 nM K_i
• Löslichkeit: DMSO: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.); degassed ethanol: soluble (Dilute in aqueous medium immediately prior to use and store on ice for no more than 12 hours.)
• λmax: 224 nm
• Lagertemp.: −20°C
• SMILES String: [H]\C(Br)=C1\CCC(C(=O)O1)c2cccc3ccccc23
• InChI: 1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+
• InChIKey: BYUCSFWXCMTYOI-ZRDIBKRKSA-N

Beschreibung

Biochem./physiol. Wirkung

Potent, irreversible inhibitor of calcium-independent phospholipase A₂ and of magnesium-dependent phosphatidate phosphohydrolase from P388D macrophages (IC₅₀ = 8 μM); enzyme activated irreversible chymotrypsin inhibitor (K_i = 636 nM).

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves