AV35095

Anti-KCNN1 antibody produced in rabbit

IgG fraction of antiserum

• MDL-Nummer: MFCD06798511
• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: IgG fraction of antiserum
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 60 kDa
• Speziesreaktivität: human
• Konzentration: 0.5 mg - 1 mg/mL
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NP_002239
• UniProt-Hinterlegungsnummer: Q6DJU4
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... KCNN1(3780)

Beschreibung

Allgemeine Beschreibung

KCNN1 (SK1) codes for a voltage-independent, calcium-activated channel integral membrane protein. This protein belongs to potassium channel family. Mouse SK1 protein can interact with calmodulin without the aid of Ca²⁺ ions.
Rabbit Anti-KCNN1 antibody recognizes human and bovine KCNN1.

Immunogen

Synthetic peptide directed towards the C terminal region of human KCNN1

Anwendung

Rabbit Anti-KCNN1 antibody is suitable for western blot applications at a concentration of 1.25 μg/ml.

Biochem./physiol. Wirkung

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. KCNN1 is a member of the KCNN family of potassium channels.

Sequenz

Synthetic peptide located within the following region: KIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEARLATLESRLD

Physikalische Form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable