A9605

AC-93253

≥98% (HPLC)

• Synonym(e): 2-[3-(1,3-Dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-3-ethyl-benzothiazolium iodide
• Empirische Formel (Hill-System): C₂₃H₂₅N₂SI
• CAS-Nummer: 108527-83-9
• Molekulargewicht: 488.43
• MDL-Nummer: MFCD03769029
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24724406

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: solid
• Lagerbedingungen: desiccated
• Farbe: dark purple
• Löslichkeit: DMSO: >10 mg/mL; H₂O: insoluble
• Lagertemp.: 2-8°C
• SMILES String: [I-].CC[n+]1c(\C=C\C=C2\N(C)c3ccccc3C2(C)C)sc4ccccc14
• InChI: 1S/C23H25N2S.HI/c1-5-25-19-13-8-9-14-20(19)26-22(25)16-10-15-21-23(2,3)17-11-6-7-12-18(17)24(21)4;/h6-16H,5H2,1-4H3;1H/q+1;/p-1
• InChIKey: TWBRXRGFFUATNI-UHFFFAOYSA-M

Beschreibung

Biochem./physiol. Wirkung

AC-93253 is a potent, cell permeable, subtype selective RAR (RARα) agonist. EC₅₀ = 6.3 μM. AC-93253 has high selectivity; 89% for RARα vs 67% for RARβ1, 35% for RARβ2, and 11% for RARγ.

Leistungsmerkmale und Vorteile

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable