A1910

(±)-2-Amino-4-Phosphonobuttersäure

solid

• Synonym(e): (±)-AP-4
• Empirische Formel (Hill-System): C₄H₁₀NO₅P
• CAS-Nummer: 20263-07-4
• Molekulargewicht: 183.10
• MDL-Nummer: MFCD00013999
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 57653830
• NACRES: NA.32

Eigenschaften

• Form: solid
• Farbe: white
• SMILES String: NC(CCP(O)(O)=O)C(O)=O
• InChI: 1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)
• InChIKey: DDOQBQRIEWHWBT-UHFFFAOYSA-N
• Angaben zum Gen: human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRINA(2907) ; rat ... Grin2b(24410)

Beschreibung

Allgemeine Beschreibung

(±)-2-Amino-4-phosphonobutyric acid or DL-AP4 is a group III nonselective metabotropic glutamate receptor (mGluR) agonist. L-2-amino-4-phosphonobutyric acid (L-Ap4) displays close to 500-fold selectivity for group III mGluRs.

Anwendung

(±)-2-Amino-4-phosphonobutyric acid may be used as a glutamic acid receptor blocker in perfusion solution in the eye tissue electroretinography studies.

Biochem./physiol. Wirkung

NMDA glutamate receptor antagonist.

Vorsicht

Hygroscopic, store desiccated.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves