A1346

3-[N,N-Dimethyl-(3-myristoylaminopropyl)-ammonio]-propansulfonat

• Synonym(e): ASB-14, Amidosulfobetain-14
• Empirische Formel (Hill-System): C₂₂H₄₆N₂O₄S
• CAS-Nummer: 216667-08-2
• Molekulargewicht: 434.68
• MDL-Nummer: MFCD03456122
• UNSPSC-Code: 12161902
• NACRES: NA.28

Eigenschaften

• Beschreibung: zwitterionic
• Assay: ≥95.0% (HPLC)
• Form: powder
• Mol-Gew.: average mol wt >10,000
• Aggregatnummer: ≥23
• Lagertemp.: 2-8°C
• InChI: 1S/C22H46N2O4S/c1-4-5-6-7-8-9-10-11-12-13-14-17-22(25)23-18-15-19-24(2,3)20-16-21-29(26,27)28/h4-21H2,1-3H3,(H-,23,25,26,27,28)
• InChIKey: UTSXERRKRAEDOV-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

ASB-14 comprises alkyl tails and amidosulfobetaine headgroup.

Anwendung

ASB-14 has been used as a component of rehydration buffer for proteomic sample preparation from Leishmania donovani.

Zwitterionisches Waschmittel für die Auflösung von Proteinen für die Bestimmung mittels 2D-Elektrophorese

Biochem./physiol. Wirkung

ASB-14 is useful in proteasome extraction especially for the membrane associated proteins. Along with CHAPS (3-(3-cholamidopropyl)dimethylammonio)-1-propanesulfonate), it is employed in protein solubilization even in the presence of thiourea.

Hinweis zur Analyse

ASB-14 (amidosulfobetaine-14), a membrane solubilizing zwitterionic detergent (medium chain amidosulfobetaine surfactant), may be used in protein and macromolecule research for the preparative extraction and solubilization of proteins for separation and analysis by methods such as 2D-electrophoresis. ASB-14 may be used in tissue engineering for antigen removal (AR) for xenogeneic scaffold generation. ASB-14 may be used to develop and study zwitterionic micelles.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)