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Sigma-Aldrich

6-(7-Nitrobenzofurazan-4-ylamino)hexansäure

suitable for fluorescence

Synonym(e):

6-(7-Nitro-2,1,3-benzoxadiazol-4-ylamino)-hexansäure

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About This Item

Empirische Formel (Hill-System):
C12H14N4O5
CAS-Nummer:
88235-25-0
Molekulargewicht:
294.26
Beilstein:
6936249
MDL-Nummer:
MFCD00057884
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329764495
NACRES:
NA.32

Assay

≥96.0% (HPLC)

Qualitätsniveau

100

Form

powder

Fluoreszenz

λex 466 nm; λem 535 nm in methanol

Eignung

suitable for fluorescence

SMILES String

OC(=O)CCCCCNc1ccc([N+]([O-])=O)c2nonc12

InChI

1S/C12H14N4O5/c17-10(18)4-2-1-3-7-13-8-5-6-9(16(19)20)12-11(8)14-21-15-12/h5-6,13H,1-4,7H2,(H,17,18)

InChIKey

DJFNQJJTTPMBIL-UHFFFAOYSA-N

Sonstige Hinweise

Probing of the binding sites of fatty acid and sterol carrier proteins

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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D W Dekkers et al.
The Biochemical journal, 350 Pt 2, 531-535 (2000-08-19)
The role of multidrug resistance protein 1 (MRP1) in the maintenance of transbilayer lipid asymmetry in the erythrocyte membrane was investigated. The transbilayer distribution of endogenous phospholipids and [(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]hexanoyl (NBD)-labelled lipid analogues was compared in the absence and the presence
J C McIntyre et al.
Chemistry and physics of lipids, 66(3), 171-180 (1993-12-01)
The synthesis, identification and characterization of neutral lipid analogs containing N-(7-nitro-2,1,3-benzoxadiazoi-4-yl)-aminocaproic acid are reported. The acyl-imidazole derivative of the fluorescent fatty acid was used to esterify L-alpha-glycerophosphorylcholine. Fluorescent phosphatidylcholines were converted to the corresponding diacylglycerols by phospholipase C digestion. Triacylglycerols
S Lin et al.
Photochemistry and photobiology, 54(3), 361-365 (1991-09-01)
The fluorescence kinetics of the nitrobenzoxadiazole (NBD) chromophore were studied at low concentrations in solvents with varying polarity and hydrogen-bonding donor strength. The emission decay was essentially single exponential in all solvents studied. While the absorption and fluorescence solvatochromism is
S J Slater et al.
Biochemistry, 32(14), 3714-3721 (1993-04-13)
It is proposed that increased phospholipid unsaturation in membranes and perturbation by agents such as ethanol weaken interlipid hydrogen bonding involving water and that the process is independent of effects on lipid order. To investigate this, the rates of phospholipid
A Sofer et al.
Journal of cell science, 109 ( Pt 8), 2111-2119 (1996-08-01)
In order to study the endocytosis of membrane lipids during the development of neuronal polarity, we examined the internalization of a short acyl chain fluorescent derivative of ganglioside GM1, N-(6-(4-nitrobenz-2-oxa-1,3-diazole-7-yl)-aminohexanoyl)-GM1 (C6-NBD-GM1), in hippocampal neurons cultured at low density. C6-NBD-GM1 was
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