61760

Lektin aus Canavalia ensiformis

lyophilized, ≥50% (GE), powder

• Synonym(e): Con A, Concanavalin A aus Jack Bean
• MDL-Nummer: MFCD00071069
• UNSPSC-Code: 12352202
• NACRES: NA.56

Eigenschaften

• Biologische Quelle: Canavalia ensiformis
• Qualitätsniveau: 100
• Form: powder
• Qualität: lyophilized
• Mol-Gew.: M_r ~53000
• Konzentration: ≥50% (GE)
• Methode(n): XRF: suitable
• Lagertemp.: 2-8°C

Beschreibung

Biochem./physiol. Wirkung

Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca²⁺ and Mn²⁺ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable