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Merck

53379

Sigma-Aldrich

FITC-CM-Dextran

average mol wt 40,000

Synonym(e):

FITC-CM-Dextran 40, Fluoresceinisothiocyanat-Carboxymethyl–Dextran

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About This Item

UNSPSC-Code:
12352108
NACRES:
NA.32

Biologische Quelle

synthetic

Qualitätsniveau

Konjugat

FITC conjugate

Form

powder or crystals

Mol-Gew.

average mol wt 40,000

Zusammensetzung

carboxymethyl content, 3-7%

Kennzeichnungsgrad

0.001-0.020 mol/mol FITC glucose

Methode(n)

permeability assay: suitable

Fluoreszenz

λex 493 nm; λem 517 nm±5 nm in 0.1 M Tris pH 8.0

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Anwendung

FITC-CM-Dextran 40, an anionic fluorescent dextran that may be used to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery. FITC-CM-Dextran 40 may be use to compare its selectivity versus neutral FITC-Dextran 40.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Rui Liu et al.
International journal of molecular medicine, 42(5), 2903-2913 (2018-08-23)
Inflammatory bowel disease (IBD) is a multifactorial inflammatory disease, and increasing evidence has demonstrated that the mechanism of the pathogenesis of IBD is associated with intestinal epithelial barrier injury. Long non‑coding RNAs (lncRNAs) are a class of transcripts >200 nucleotides
Reduced diffusion of charge-modified, conformationally intact anionic Ficoll relative to neutral Ficoll across the rat glomerular filtration barrier in vivo.
Axelsson J, Sverrisson K, Rippe A, et al.
American Journal of Physiology: Renal Physiology, 301, F708-F712 (2011)
Carrier and dose effects on the pharmacokinetics of T-0128, a camptothecin analogue-carboxymethyl dextran conjugate, in non-tumor- and tumor-bearing rats.
Harada M, Murata J, Sakamura Y, et al.
J. Controlled Release, 71, 71-86 (2001)
Dan Zhang et al.
Journal of cellular physiology, 233(1), 688-698 (2017-03-23)
Understanding the role and underlying regulation mechanism of autophagy in lipopolysaccharide-induced lung injury (LPS-LI) may provide potentially new pharmacological targets for treatment of acute lung injury. The aim of this study was to investigate the functional significance of autophagy in
Chichi Li et al.
Cell death & disease, 10(11), 804-804 (2019-10-28)
Adipose-derived stem cells (ADSCs) have been shown to be beneficial in some pulmonary diseases, and the paracrine effect is the major mechanism underlying ADSC-based therapy. Autophagy plays a crucial role in maintaining stem cell homeostasis and survival. However, the role

Artikel

Additional information about FITC-labelled polysaccarides including FITC-Dextran, FITC-DEAE-dextran (FDD), FITC-carboxymethyl-dextran (FCM-Dextran). This page discusses the impact of weight-average molecular weight on the respective molecule dimensions and other physical properties

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