483R-1

p40 (ZR8) Rabbit Monoclonal Antibody

• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100; 500
• Konjugat: unconjugated
• Antikörperform: culture supernatant
• Antikörper-Produkttyp: primary antibodies
• Klon: ZR8
• Beschreibung: For In Vitro Diagnostic Use in Select Regions
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Verpackung: vial of 0.1 mL concentrate (483R-14); vial of 0.1 mL concentrate, Research Use Only (483R-14-RUO); vial of 0.5 mL concentrate (483R-15); vial of 1.0 mL concentrate (483R-16); vial of 1.0 mL concentrate, Research Use Only (483R-16-RUO); vial of 1.0 mL pre-dilute, Research Use Only (483R-17-RUO); vial of 1.0 mL pre-dilute, ready to use (483R-17); vial of 25.0 mL pre-dilute, ready-to-use (483R-10); vial of 25.0 mL pre-dilute, ready-to-use, Research Use Only (483R-10-RUO); vial of 7.0 mL pre-dilute, ready to use (483R-18); vial of 7.0 mL pre-dilute, ready to use, Research Use Only (483R-18-RUO)
• Hersteller/Markenname: Cell Marque
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable (1:100-1:200 (concentrated))
• Isotyp: IgG
• Kontrolle: lung (squamous cell carcinoma), prostate, urothelial carcinoma
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Visualisierung: nuclear

Beschreibung

Allgemeine Beschreibung

p40 is an isoform of p63, a transcription factor that regulates many cell activities, including cell proliferation, maintenance, and differentiation. It performs as a sensitive and specific tool for aiding in the identification of squamous cell carcinoma of the lung. In addition to its utility as a squamous differentiation marker, p40 has also been proven to be a valuable marker for highlighting myoepithelial and basal cell populations in prostate, breast, skin, and salivary gland.^1-5 Strong p40 expression is frequently observed in esophageal cancerous squamous lesions.⁶ Immunohistochemical detection of p40 can also be helpful in identifying urothelial carcinoma.⁷ In cases of prostate carcinoma, p40 is almost always found to be negative for basal cell staining.⁸

Qualität

• United States - IVD
• Canada - RUO
• European Union - IVD
• Japan - RUO

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Angaben zur Herstellung

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Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable