466R-1

SDHB (EP288) Rabbit Monoclonal Primary Antibody

• Synonym(e): Succinate dehydrogenase B
• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100; 500
• Konjugat: unconjugated
• Antikörperform: culture supernatant
• Antikörper-Produkttyp: primary antibodies
• Klon: EP288, monoclonal
• Beschreibung: For In Vitro Diagnostic Use in Select Regions
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Verpackung: vial of 0.1 mL concentrate (466R-14); vial of 0.1 mL concentrate Research Use Only (466R-14-RUO); vial of 0.5 mL concentrate (466R-15); vial of 1.0 mL concentrate (466R-16); vial of 1.0 mL concentrate Research Use Only (466R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (466R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (466R-17); vial of 7.0 mL pre-dilute ready-to-use (466R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (466R-18-RUO)
• Hersteller/Markenname: Cell Marque^™
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotyp: IgG
• Kontrolle: GIST
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Visualisierung: cytoplasmic
• Angaben zum Gen: human ... SDHB(6390)

Beschreibung

Allgemeine Beschreibung

Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane. Many cancers are generally positive for SDHB, including renal cell carcinomas (RCC) and gastrointestinal stromal tumors (GIST). However, a subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.

Qualität

IVD

IVD

IVD

RUO

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Angaben zur Herstellung

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Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable