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Merck

347M-1

Sigma-Aldrich

Vimentin (V9) Mouse Monoclonal Antibody

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100
500

Konjugat

unconjugated

Antikörperform

ascites fluid

Antikörper-Produkttyp

primary antibodies

Klon

V9, monoclonal

Beschreibung

For In Vitro Diagnostic Use in Select Regions (See Chart)

Form

buffered aqueous solution

Speziesreaktivität

human

Verpackung

vial of 0.1 mL concentrate (347M-14)
vial of 0.5 mL concentrate (347M-15)
bottle of 1.0 mL predilute (347M-17)
vial of 1.0 mL concentrate (347M-16)
bottle of 7.0 mL predilute (347M-18)

Hersteller/Markenname

Cell Marque®

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotyp

IgGκ

Kontrolle

tonsil

Versandbedingung

wet ice

Lagertemp.

2-8°C

Visualisierung

cytoplasmic

Angaben zum Gen

human ... VIM(7431)

Allgemeine Beschreibung

Anti-vimentin is of limited value as a diagnostic tool; however, when used in combination with other antibodies (in panels) it is useful for the subclassification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. This antibody recognizes a 57 kD intermediate filament. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.

Qualität


IVD

IVD

IVD

RUO

Verlinkung

Vimentin Positive Control Slides, Product No. 347S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Angaben zur Herstellung

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Kunden haben sich ebenfalls angesehen

A Ben-Ze'ev
The Journal of cell biology, 99(4 Pt 1), 1424-1433 (1984-10-01)
The expression of cytokeratins and vimentin was investigated in Madin-Darby bovine epithelial cells (MDBK) in culture under conditions of varied cell spreading and cell-cell contact. When extensive cell-cell contact was achieved by seeding cells at high density in monolayer, or
E B Lane et al.
Nature, 303(5919), 701-704 (1983-06-23)
Of the five classes of intermediate filaments found in vertebrate tissues, the cytokeratins are considered unique to epithelial tissues, while vimentin is expressed by endothelial and mesenchymal cells. In neither case is the precise function of the filament system known.
I Takeyoshi et al.
Hepato-gastroenterology, 47(36), 1611-1614 (2001-01-10)
Carcinosarcomas are rare tumors, which are usually composed of carcinomatous areas close to or intermixed with sarcomatous components. Only 6 cases of carcinosarcoma of the colon have been reported in the English literature previously. We describe the 7th case, an
M Leader et al.
Histopathology, 11(1), 63-72 (1987-01-01)
In this study we examined 198 sarcomas, 38 carcinomas, 13 'tumours with a spindle cell component' and 22 malignant melanomas with a commercial monoclonal vimentin antibody. All histopathological material was formalin fixed and paraffin embedded. The results show this antibody
H Battifora
American journal of clinical pathology, 96(5), 669-671 (1991-11-01)
Monitoring of the quality of antigen preservation and the uniformity of tissue fixation in paraffin-embedded, formaldehyde-fixed tissues is facilitated by the routine use of an antibody to an epitope of vimentin that is partially susceptible to formaldehyde fixation. Other diagnostically

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