Y0000109

Thiomersal

European Pharmacopoeia (EP) Reference Standard

• Synonym(e): 2-(Ethylmercurimercapto)-benzoesäure Natriumsalz, Merthiolate^® Natriumsalz, Natriumethylmercurithiosalicylat, Quecksilber-([o-carboxyphenyl]thio)-ethyl Natriumsalz
• Lineare Formel: 2-(C₂H₅HgS)C₆H₄CO₂Na
• CAS-Nummer: 54-64-8
• Molekulargewicht: 404.81
• Beilstein: 8169555
• MDL-Nummer: MFCD00013062
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329830849
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: thimerosal
• Hersteller/Markenname: EDQM
• mp (Schmelzpunkt): 234-237 °C (dec.) (lit.)
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: [Na+].CC[Hg]Sc1ccccc1C([O-])=O
• InChI: 1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
• InChIKey: RTKIYNMVFMVABJ-UHFFFAOYSA-L

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Thimerosal EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem./physiol. Wirkung

Thimerosal ist ein Sulfhydryl (Thiol)-oxidierendes Reagens, das eine Vielzahl von Sulfhydryl-abhängigen Enzymen und Proteinen wie PI3-Kinase-abhängige Methionin-Synthase, Glutamattransportrezeptoren und Na⁺+K⁺-abhängige ATPasen hemmen kann.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Haftungsausschluss

As part of the corporation global plan to support the Minamata Convention in eliminating mercury-containing compounds, as of January 2021 customers will be required to provide an End-Use Declaration. The sales of thimerosal will be restricted for approved applications only, such as preservative in vaccine manufacturing, preservative in eye cosmetics, research use within academia (excluding preservation intent) and as reference material only.

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act , European Biocidal Products Regulation, Canada′s Pest Management Regulatory Agency, Turkey′s Biocidal Products Regulation, Korea′s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H300 + H310 + H330,H373,H410
• P-Sätze: P262 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Gefahreneinstufungen: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral
• Zielorgane: Kidney
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable