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Y0000042

Josamycinpropionat

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

Leucomycin V 3-acetat-4B-(3-methylbutanoat)-2A-propanoat

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About This Item

Empirische Formel (Hill-System):
C45H73N1O16
CAS-Nummer:
Molekulargewicht:
884.06
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

josamycin

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Versandbedingung

wet ice

Lagertemp.

−20°C

SMILES String

N(C1C(C(OC(C1OC3OC(C(C(C3)(O)C)OC(=O)CC(C)C)C)C)OC2C(C(CC(=O)OC(C\C=C\C=C/C(C(CC2CC=O)C)O)C)OC(=O)C)OC)OC(=O)CC)(C)C

InChI

1S/C45H73NO16/c1-13-34(50)59-42-38(46(10)11)39(61-37-24-45(9,53)43(29(7)56-37)60-35(51)21-25(2)3)28(6)57-44(42)62-40-31(19-20-47)22-26(4)32(49)18-16-14-15-17-27(5)55-36(52)23-33(41(40)54-12)58-30(8)48/h14-16,18,20,25-29,31-33,37-44,49,53H,13,17,19,21-24H2,1-12H3/b15-14+,18-16-

InChIKey

NBWASFCRCRXRKF-HHKVLAKUSA-N

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Josamycin propionate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

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M Ducci et al.
International journal of clinical pharmacology research, 4(3), 195-199 (1984-01-01)
In this study a new high-pressure liquid chromatographic method for monitoring plasma levels of josamycin is described. Josamycin propionate was used as the internal standard. After being extracted from plasma by chloroform at an alkaline pH, the compounds were easily
Cindy Govaerts et al.
Journal of mass spectrometry : JMS, 39(4), 437-446 (2004-04-23)
Coupled liquid chromatography and ion trap mass spectrometry (LC/MS) was used for the characterization of the semi-synthetic 16-membered ring macrolide josamycin propionate. On-line identification of impurities in this antibiotic complex was performed with an ion trap mass spectrometer without recourse
G Privitera et al.
International journal of clinical pharmacology research, 4(3), 201-207 (1984-01-01)
Josamycin propionate, a tasteless josamycin derivative suitable for the preparation of paediatric oral suspension, was employed in a large, multicentre clinical study aimed at evaluating the effectiveness and safety of the drug. Two hundred paediatric practitioners participated in the study

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