SMB01348

Dihydrocortisol

≥95% (HPLC)

• Synonym(e): 5β-Pregnane-11β,17α,21-triol-3,20-dione, 11β,17,21-Trihydroxy-5β-pregnane-3,20-dione, 11β,17α,21-Trihydroxy-5β-pregnane-3,20-dione, 5β-Dihydrocortisol
• Empirische Formel (Hill-System): C₂₁H₃₂O₅
• CAS-Nummer: 1482-50-4
• Molekulargewicht: 364.48
• MDL-Nummer: MFCD00070050
• UNSPSC-Code: 51420000

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥95% (HPLC)
• Form: solid
• Lagertemp.: 2-8°C
• SMILES String: O[C@]1([C@@]2([C@H]([C@H]3[C@@H]([C@@]4([C@H](CC3)CC(=O)CC4)C)[C@H](C2)O)CC1)C)C(=O)CO
• InChI: 1S/C21H32O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12,14-16,18,22,24,26H,3-11H2,1-2H3/t12-,14+,15+,16+,18-,19+,20+,21+/m1/s1
• InChIKey: ACSFOIGNUQUIGE-AIPUTVCKSA-N

Beschreibung

Allgemeine Beschreibung

5β-Dihydrocortisol is the product of the enzyme steroid 5-beta-reductase, which catalyzes the reduction of progesterone, androstenedione, 17-alpha-hydroxyprogesterone, testosterone, aldosterone, corticosterone, and cortisol to 5-beta-reduced metabolites. 5β-Dihydrocortisol has shown to potentiate the action of topically applied dexamethasone in raising the intraocular pressure in young rabbits.

Anwendung

Metabolomics research

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H360FD,H373
• P-Sätze: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Repr. 1A - STOT RE 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3