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Merck

PHR1919

Supelco

Chlorzoxazon

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

Chlorzoxazon, 5-Chlor-2(3H)-benzoxazolon

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About This Item

Empirische Formel (Hill-System):
C7H4ClNO2
CAS-Nummer:
Molekulargewicht:
169.57
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to USP 1130505

API-Familie

chlorzoxazone

Analysenzertifikat (CofA)

current certificate can be downloaded

Verpackung

pkg of 500 mg

mp (Schmelzpunkt)

191-192 °C (lit.)

Anwendung(en)

pharmaceutical

Format

neat

Lagertemp.

2-30°C

SMILES String

Clc1ccc2OC(=O)Nc2c1

InChI

1S/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10)

InChIKey

TZFWDZFKRBELIQ-UHFFFAOYSA-N

Angaben zum Gen

human ... KCNN4(3783)

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Allgemeine Beschreibung

Chlorzoxazone is a centrally active muscle relaxant used to treat painful muscle spasms linked to musculoskeletal disorders, such as fibrositis, bursitis, myositis, spondylitis, etc.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

Chlorzoxazone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography technique, spectrophotometry and fluorescence spectroscopy.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Chlorzoxazone is a skeletal muscle relaxant.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAB0913 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Second derivative synchronous fluorescence spectroscopy for the simultaneous determination of chlorzoxazone and ibuprofen in pharmaceutical preparations and biological fluids
El-Enany N, et al.
International Journal of Biomedical Science : IJBS, 5(2), 136-136 (2009)
Development and validation of spectrophotometric methods for simultaneous estimation of tramadol hydrochloride and chlorzoxazone in tablet dosage form
Puranik M, et al.
Indian Journal of Pharmaceutical Sciences, 68(6), 737-737 (2006)
Simultaneous determination of aceclofenac, paracetamol, and chlorzoxazone by RP-HPLC in pharmaceutical dosage form
Shaikh KA and Devkhile AB
Journal of Chromatographic Science, 46(7), 649-652 (2008)
Analytical Profiles of Drug Substances, 16(7), 119-144 (1987)

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