PHR1572

Oxymetazolin-Hydrochlorid

certified reference material, pharmaceutical secondary standard

• Synonym(e): Oxymetazolin -hydrochlorid, 2-(4-tert.-Butyl-3-hydroxy-2,6-dimethylbenzyl)-2-imidazolin -hydrochlorid
• Empirische Formel (Hill-System): C₁₆H₂₄N₂O · HCl
• CAS-Nummer: 2315-02-8
• Molekulargewicht: 296.84
• EG-Nummer: 219-015-0
• MDL-Nummer: MFCD00058147
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823480
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to Ph. Eur. O0290000; traceable to USP 1486004
• API-Familie: oxymetazoline
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 10 g
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-30°C
• SMILES String: Cl.Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C
• InChI: 1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H
• InChIKey: BEEDODBODQVSIM-UHFFFAOYSA-N
• Angaben zum Gen: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Oxymetazoline hydrochloride belongs to the category of non-selective adrenergic drugs commonly used as eye and nose drops.

Anwendung

Oxymetazoline hydrochloride may be used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical formulations using spectrophotometric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Oxymetazolinhydrochlorid ist ein partieller α_2A-Adrenozeptoragonist; ein Agonist an den Seotoninrezeptoren 5-HT_1A, 5-HT_1B und 5-HT_1D. Es ist ein gemischter Agonist-Antagonist an den Serotoninrezeptoren 5-HT_1C.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAB5024 in the slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Sicherheitshinweise

• Piktogramme: GHS06,GHS05
• Signalwort: Danger
• H-Sätze: H300 + H330,H318,H412
• P-Sätze: P260 - P264 - P273 - P280 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Chronic 3 - Eye Dam. 1
• Lagerklassenschlüssel: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3